Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome

Rett syndrome (RTT) is a rare neurodevelopmental disorder, characterized by severe behavioral and physiological symptoms. Mutations in the methyl CpG-binding protein 2 gene (MECP2) cause >95% of classic cases, and currently there is no cure for this devastating disorder. The serotonin receptor 7...

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Detalhes bibliográficos
Main Authors: De Filippis, Bianca, Nativio, Paola, Fabbri, Alessia, Ricceri, Laura, Adriani, Walter, Lacivita, Enza, Leopoldo, Marcello, Passarelli, Francesca, Fuso, Andrea, Laviola, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207333/
https://ncbi.nlm.nih.gov/pubmed/24809912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.105
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