Modulation of RhoGTPases Improves the Behavioral Phenotype and Reverses Astrocytic Deficits in a Mouse Model of Rett Syndrome

RhoGTPases are crucial molecules in neuronal plasticity and cognition, as confirmed by their role in non-syndromic mental retardation. Activation of brain RhoGTPases by the bacterial cytotoxic necrotizing factor 1 (CNF1) reshapes the actin cytoskeleton and enhances neurotransmission and synaptic pla...

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Bibliografski detalji
Glavni autori: De Filippis, Bianca, Fabbri, Alessia, Simone, Daiana, Canese, Rossella, Ricceri, Laura, Malchiodi-Albedi, Fiorella, Laviola, Giovanni, Fiorentini, Carla
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306877/
https://ncbi.nlm.nih.gov/pubmed/22157810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.301
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