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New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects

The pathophysiology of numerous human disorders, such as atherosclerosis, diabetes, obesity and Alzheimer's disease, is accompanied by increased production of reactive oxygen species (ROS). ROS can oxidatively damage nearly all biomolecules, including lipids, proteins and nucleic acids. In part...

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Autores principales: Annibal, Andrea, Schubert, Kristin, Wagner, Ulf, Hoffmann, Ralf, Schiller, Jürgen, Fedorova, Maria
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207196/
https://ncbi.nlm.nih.gov/pubmed/25044840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.3373
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