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New covalent modifications of phosphatidylethanolamine by alkanals: mass spectrometry based structural characterization and biological effects

The pathophysiology of numerous human disorders, such as atherosclerosis, diabetes, obesity and Alzheimer's disease, is accompanied by increased production of reactive oxygen species (ROS). ROS can oxidatively damage nearly all biomolecules, including lipids, proteins and nucleic acids. In part...

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Autori principali: Annibal, Andrea, Schubert, Kristin, Wagner, Ulf, Hoffmann, Ralf, Schiller, Jürgen, Fedorova, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207196/
https://ncbi.nlm.nih.gov/pubmed/25044840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.3373
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