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Targeted molecular therapies against epidermal growth factor receptor: Past experiences and challenges

Epidermal growth factor receptor (EGFR) has emerged as a highly attractive therapeutic target in glioblastoma (GBM) based on its high frequency of gene amplification and mutation and its identification as an upstream trigger of dysregulated cell signaling cascades that drive GBM pathophysiology. Ext...

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Bibliografische gegevens
Hoofdauteurs: Reardon, David A., Wen, Patrick Y., Mellinghoff, Ingo K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207137/
https://ncbi.nlm.nih.gov/pubmed/25342602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou232
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