Cyclic Adenosine 5′-Diphosphate Ribose Analogs without a “Southern” Ribose Inhibit ADP-ribosyl Cyclase–Hydrolase CD38

[Image: see text] Cyclic adenosine 5′-diphosphate ribose (cADPR) analogs based on the cyclic inosine 5′-diphosphate ribose (cIDPR) template were synthesized by recently developed stereo- and regioselective N1-ribosylation. Replacing the base N9-ribose with a butyl chain generates inhibitors of cADPR...

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Bibliografiske detaljer
Main Authors: Swarbrick, Joanna M., Graeff, Richard, Zhang, Hongmin, Thomas, Mark P., Hao, Quan, Potter, Barry V. L.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207131/
https://ncbi.nlm.nih.gov/pubmed/25226087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501037u
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