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Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease

It is generally assumed that the neuropathology of sporadic (late-onset or nonfamilial) Alzheimer’s disease (AD) is driven by the overproduction and spreading of first Amyloid-β(x-42) (Aβ(42)) and later hyperphosphorylated (hp)-Tau oligomeric “infectious seeds”. Hitherto, only neurons were held to m...

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Detalhes bibliográficos
Main Authors: Dal Prà, I, Chiarini, A, Pacchiana, R, Gardenal, E, Chakravarthy, B, Whitfield, J. F, Armato, U
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207075/
https://ncbi.nlm.nih.gov/pubmed/25342943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X12666140828214701
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