Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression

BACKGROUND: Nodal signalling is an absolute requirement for normal mesoderm and endoderm formation in vertebrate embryos, yet the transcriptional networks acting directly downstream of Nodal and the extent to which they are conserved is largely unexplored, particularly in vivo. Eomesodermin also pla...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Nelson, Andrew C, Cutty, Stephen J, Niini, Marie, Stemple, Derek L, Flicek, Paul, Houart, Corinne, Bruce, Ashley EE, Wardle, Fiona C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206766/
https://ncbi.nlm.nih.gov/pubmed/25277163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0081-5
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