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Helix Stability of Oligoglycine, Oligoalanine and Oligo-β-alanine Dodecamers Reflected by Hydrogen-Bond Persistence

Helices are important structural/recognition elements in proteins and peptides. Stability and conformational differences between helices composed of α- and β-amino acids as scaffolds for mimicry of helix recognition has become a theme in medicinal chemistry. Furthermore, helices formed by β-amino ac...

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Hlavní autoři: Liu, Chengyu, Ponder, Jay W., Marshall, Garland R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206583/
https://ncbi.nlm.nih.gov/pubmed/25116421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24665
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