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Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery

The high transfection efficiency of polyethylenimine (PEI) makes it an attractive potential nonviral genetic vector for gene delivery and therapy. However, the highly positive charge of PEI leads to cytotoxicity and limits its application. To reduce the cytotoxicity of PEI, we prepared anion-enriche...

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Detalhes bibliográficos
Main Authors: Huang, Xianzhang, Shen, Sujing, Zhang, Zhanfeng, Zhuang, Junhua
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206394/
https://ncbi.nlm.nih.gov/pubmed/25342902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S61910
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