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Cross-linked polyethylenimine–tripolyphosphate nanoparticles for gene delivery

The high transfection efficiency of polyethylenimine (PEI) makes it an attractive potential nonviral genetic vector for gene delivery and therapy. However, the highly positive charge of PEI leads to cytotoxicity and limits its application. To reduce the cytotoxicity of PEI, we prepared anion-enriche...

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Hlavní autoři: Huang, Xianzhang, Shen, Sujing, Zhang, Zhanfeng, Zhuang, Junhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206394/
https://ncbi.nlm.nih.gov/pubmed/25342902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S61910
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