Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases.

Most helicases studied to date have been characterized as oligomeric, but the relation between their structure and function has not been understood. The bacteriophage T7 gene 4 helicase/primase proteins act in T7 DNA replication. We have used electron microscopy, three-dimensional reconstruction, an...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Egelman, E H, Yu, X, Wild, R, Hingorani, M M, Patel, S S
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1995
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731998/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3869
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