Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases.

Most helicases studied to date have been characterized as oligomeric, but the relation between their structure and function has not been understood. The bacteriophage T7 gene 4 helicase/primase proteins act in T7 DNA replication. We have used electron microscopy, three-dimensional reconstruction, an...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Egelman, E H, Yu, X, Wild, R, Hingorani, M M, Patel, S S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731998/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3869
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