Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures

Human motor neurons derived from embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are a potentially important tool for studying motor neuron survival and pathological cell death. However, their basic survival requirements remain poorly characterized. Here, we sought to optimize a robu...

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Main Authors: Lamas, Nuno Jorge, Johnson-Kerner, Bethany, Roybon, Laurent, Kim, Yoon A., Garcia-Diaz, Alejandro, Wichterle, Hynek, Henderson, Christopher E.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206291/
https://ncbi.nlm.nih.gov/pubmed/25337699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110324
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