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Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages.

Human macrophages are believed to damage host tissues in chronic inflammatory disease states, but these cells have been reported to express only modest degradative activity in vitro. However, while examining the ability of human monocytes to degrade the extracellular matrix component elastin, we ide...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Reddy, V Y, Zhang, Q Y, Weiss, S J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731994/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3849
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