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Linear Amplification Mediated PCR – Localization of Genetic Elements and Characterization of Unknown Flanking DNA

Linear-amplification mediated PCR (LAM-PCR) has been developed to study hematopoiesis in gene corrected cells of patients treated by gene therapy with integrating vector systems. Due to the stable integration of retroviral vectors, integration sites can be used to study the clonal fate of individual...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gabriel, Richard, Kutschera, Ina, Bartholomae, Cynthia C, von Kalle, Christof, Schmidt, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205898/
https://ncbi.nlm.nih.gov/pubmed/24998871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51543
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