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Linear Amplification Mediated PCR – Localization of Genetic Elements and Characterization of Unknown Flanking DNA

Linear-amplification mediated PCR (LAM-PCR) has been developed to study hematopoiesis in gene corrected cells of patients treated by gene therapy with integrating vector systems. Due to the stable integration of retroviral vectors, integration sites can be used to study the clonal fate of individual...

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Autori principali: Gabriel, Richard, Kutschera, Ina, Bartholomae, Cynthia C, von Kalle, Christof, Schmidt, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205898/
https://ncbi.nlm.nih.gov/pubmed/24998871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51543
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