Translational assessment of mitochondrial dysfunction of pancreatic cancer from in vitro gene microarray and animal efficacy studies, to early clinical studies, via the novel tumor-specific anti-mitochondrial agent, CPI-613

STUDY RATIONALE AND OBJECTIVES: Via genetic alterations, malignant transformation and proliferation are associated with extensive alterations of mitochondrial energy metabolism of tumor cells. Thus, inhibition of the altered form of mitochondrial energy metabolism of tumor cells may be an effective...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lee, King C., Maturo, Claudia, Perera, Candida N., Luddy, John, Rodriguez, Robert, Shorr, Robert
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2014
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205874/
https://ncbi.nlm.nih.gov/pubmed/25405166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2014.05.08
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars