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Novel Adeno-associated Viruses Derived From Pig Tissues Transduce Most Major Organs in Mice

Recently, development of Adeno-associated virus (AAV) vectors has been focusing on expanding the genetic diversity of vectors from existing sequences via directed evolution or epitope remapping. Apart from intelligent design, AAV isolation from natural sources remains an important source of new AAVs...

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Detalhes bibliográficos
Main Authors: Bello, Alexander, Chand, Allan, Aviles, Jenna, Soule, Geoff, Auricchio, Alberto, Kobinger, Gary P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205840/
https://ncbi.nlm.nih.gov/pubmed/25335510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06644
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