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Tsc1 promotes the differentiation of memory CD8(+) T cells via orchestrating the transcriptional and metabolic programs

Memory CD8(+) T cells are an essential component of protective immunity. Signaling via mechanistic target of rapamycin (mTOR) has been implicated in the regulation of the differentiation of effector and memory T cells. However, little is understood about the mechanisms that control mTOR activity, or...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shrestha, Sharad, Yang, Kai, Wei, Jun, Karmaus, Peer W. F., Neale, Geoffrey, Chi, Hongbo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205612/
https://ncbi.nlm.nih.gov/pubmed/25271321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404264111
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