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Bordetella pertussis pathogenesis: current and future challenges

Pertussis, or whooping cough, has recently reemerged as a major public health threat despite high levels of vaccination against the etiological agent, Bordetella pertussis. In this Review, we describe the pathogenesis of this disease, with a focus on recent mechanistic insights into virulence factor...

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Detalhes bibliográficos
Main Authors: Melvin, Jeffrey A., Scheller, Erich V., Miller, Jeff F., Cotter, Peggy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205565/
https://ncbi.nlm.nih.gov/pubmed/24608338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro3235
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