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Targeting hepatitis B virus antigens to dendritic cells by heat shock protein to improve DNA vaccine potency

AIM: To investigate a novel DNA vaccination based upon expression of the HBV e antigen fused to a heat shock protein (HSP) as a strategy to enhance DNA vaccine potency. METHODS: A pCMV-HBeAg-HSP DNA vaccine and a control DNA vaccine were generated. Mice were immunized with these different construct....

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Hlavní autoři: Gu, Qin-Long, Huang, Xue, Ren, Wen-Hong, Shen, Lei, Liu, Bing-Ya, Chen, Si-Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Co., Limited 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205437/
https://ncbi.nlm.nih.gov/pubmed/17990356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i44.5911
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