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Targeting hepatitis B virus antigens to dendritic cells by heat shock protein to improve DNA vaccine potency
AIM: To investigate a novel DNA vaccination based upon expression of the HBV e antigen fused to a heat shock protein (HSP) as a strategy to enhance DNA vaccine potency. METHODS: A pCMV-HBeAg-HSP DNA vaccine and a control DNA vaccine were generated. Mice were immunized with these different construct....
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Baishideng Publishing Group Co., Limited
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205437/ https://ncbi.nlm.nih.gov/pubmed/17990356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i44.5911 |
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