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Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2

AIM: To evaluate the effects of NS-398, a cyclooxygenase-2 (COX-2) inhibitor, on the proliferation and apoptosis of HepG2 cells. METHODS: The effects of NS-398 on the proliferation of HepG2 cells were evaluated by MTT. DNA fragmentation gel analysis was used to analyze the apoptotic cells. DNA ploid...

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Detalhes bibliográficos
Main Authors: Huang, Dong-Sheng, Shen, Ke-Zhen, Wei, Jian-Feng, Liang, Ting-Bo, Zheng, Shu-Sen, Xie, Hai-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205402/
https://ncbi.nlm.nih.gov/pubmed/15633216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i2.204
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