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Continuous requirement for the T cell receptor for regulatory T cell function
Foxp3(+) regulatory T cells (T(reg) cells) maintain immunological tolerance and their deficiency results in fatal multi-organ autoimmunity. Although heightened T cell receptor (TCR) signaling is critical for the differentiation of T(reg) cells, the role of TCR signaling in T(reg) cell function remai...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205268/ https://ncbi.nlm.nih.gov/pubmed/25263123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3004 |
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