Orthotopic models of pediatric brain tumors in zebrafish

High-throughput screens (HTS) of compound toxicity against cancer cells can identify thousands of potential new drug-leads. But only limited numbers of these compounds can progress to expensive and labor intensive efficacy studies in mice, creating a ‘bottle-neck’ in the drug development pipeline. A...

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Hlavní autoři: Eden, Christopher J., Ju, Bensheng, Murugesan, Mohankumar, Phoenix, Timothy, Nimmervoll, Birgit, Tong, Yiai, Ellison, David W., Finkelstein, David, Wright, Karen, Boulos, Nidal, Dapper, Jason, Thiruvenkatam, Radhika, Lessman, Charles, Taylor, Michael R., Gilbertson, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205223/
https://ncbi.nlm.nih.gov/pubmed/24747973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.107
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