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Direct estradiol and diethylstilbestrol actions on early- vs. late-stage prostate cancer cells

BACKGROUND: Diethylstilbestrol (DES) and other pharmaceutical estrogens have been used at ≥μM concentrations to treat advanced prostate tumors, with successes primarily attributed to indirect hypothalamic-pituitary-testicular axis control mechanisms. However, estrogens also directly affect tumor cel...

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Bibliografiske detaljer
Main Authors: Koong, Luke Y., Watson, Cheryl S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205220/
https://ncbi.nlm.nih.gov/pubmed/25213831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22875
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