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Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers

Transcription factors control the fate of a cell by regulating the expression of genes and regulatory networks. Recent successes in inducing pluripotency in terminally differentiated cells as well as directing differentiation with natural transcription factors has lent credence to the efforts that a...

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Autori principali: Eguchi, Asuka, Lee, Garrett O., Wan, Fang, Erwin, Graham S., Ansari, Aseem Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205157/
https://ncbi.nlm.nih.gov/pubmed/25145439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140400
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