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Rhamnose Glycoconjugates for the Recruitment of Endogenous Anti-carbohydrate Antibodies to Tumor Cells

Immunotherapy is a promising strategy for targeting tumors. One emerging approach is to harness the immune effector functions of natural antibodies to destroy tumor cells. Dinitrophenyl (DNP) and the galactose-α-1,3-galactose (αGal) epitope are two haptens that bind endogenous antibodies. One potent...

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Detalhes bibliográficos
Main Authors: Sheridan, Rachael T. C., Hudon, Jonathan, Hank, Jacquelyn A., Sondel, Paul M., Kiessling, Laura L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205123/
https://ncbi.nlm.nih.gov/pubmed/24909955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402019
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