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A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen–based DNA minigene vaccines
A lack of relevant animal models has hampered preclinical screening and critical evaluation of the efficacy of human vaccines in vivo. Carcinoembryonic antigen–A2Kb (CEA–A2Kb) double transgenic mice provide a biologically relevant model for preclinical screening and critical evaluation of human CEA...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC420510/ https://ncbi.nlm.nih.gov/pubmed/15199414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421107 |
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