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Interactions of “Bora-Penicilloates” with Serine β-Lactamases and DD-Peptidases

[Image: see text] Specific boronic acids are generally powerful tetrahedral intermediate/transition state analogue inhibitors of serine amidohydrolases. This group of enzymes includes bacterial β-lactamases and DD-peptidases where there has been considerable development of boronic acid inhibitors. T...

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Bibliographische Detailangaben
Hauptverfasser: Dzhekieva, Liudmila, Adediran, S. A., Pratt, R. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204886/
https://ncbi.nlm.nih.gov/pubmed/25302576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500970f
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