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Deacylation Transition States of a Bacterial DD-Peptidase

β-Lactam antibiotics restrict bacterial growth by inhibition of DD-peptidases. These enzymes catalyze the final transpeptidation step in bacterial cell wall biosynthesis. Although much structural information is now available for these enzymes, the mechanism of the actual transpeptidation reaction ha...

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Detalhes bibliográficos
Main Authors: Adediran, S.A., Kumar, I., Pratt, R.F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2512701/
https://ncbi.nlm.nih.gov/pubmed/17059224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061341d
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