HDAC1 Controls CD8(+) T Cell Homeostasis and Antiviral Response

Reversible lysine acetylation plays an important role in the regulation of T cell responses. HDAC1 has been shown to control peripheral T helper cells, however the role of HDAC1 in CD8(+) T cell function remains elusive. By using conditional gene targeting approaches, we show that LckCre-mediated de...

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Hlavní autoři: Tschismarov, Roland, Firner, Sonja, Gil-Cruz, Cristina, Göschl, Lisa, Boucheron, Nicole, Steiner, Günter, Matthias, Patrick, Seiser, Christian, Ludewig, Burkhard, Ellmeier, Wilfried
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204873/
https://ncbi.nlm.nih.gov/pubmed/25333902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110576
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