Role of promoter hypermethylation in Cisplatin treatment response of male germ cell tumors

BACKGROUND: Male germ cell tumor (GCT) is a highly curable malignancy, which exhibits exquisite sensitivity to cisplatin treatment. The genetic pathway(s) that determine the chemotherapy sensitivity in GCT remain largely unknown. RESULTS: We studied epigenetic changes in relation to cisplatin respon...

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Bibliographic Details
Main Authors: Koul, Sanjay, McKiernan, James M, Narayan, Gopeshwar, Houldsworth, Jane, Bacik, Jennifer, Dobrzynski, Deborah L, Assaad, Adel M, Mansukhani, Mahesh, Reuter, Victor E, Bosl, George J, Chaganti, Raju SK, Murty, Vundavalli VVS
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC420487/
https://ncbi.nlm.nih.gov/pubmed/15149548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-16
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