Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression

BACKGROUND: Cervical Cancer (CC) exhibits highly complex genomic alterations. These include hemizygous deletions at 4p15.3, 10q24, 5q35, 3p12.3, and 11q24, the chromosomal sites of Slit-Robo pathway genes. However, no candidate tumor suppressor genes at these regions have been identified so far. Sli...

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Bibliografiska uppgifter
Huvudupphovsmän: Narayan, Gopeshwar, Goparaju, Chandra, Arias-Pulido, Hugo, Kaufmann, Andreas M, Schneider, Achim, Dürst, Matthias, Mansukhani, Mahesh, Pothuri, Bhavana, Murty, Vundavalli V
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2006
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482714/
https://ncbi.nlm.nih.gov/pubmed/16700909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-16
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