Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha

BACKGROUND: Copy number gains and amplifications are characteristic feature of cervical cancer (CC) genomes for which the underlying mechanisms are unclear. These changes may possess oncogenic properties by deregulating tumor-related genes. Gain of short arm of chromosome 5 (5p) is the most frequent...

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Detalhes bibliográficos
Main Authors: Scotto, Luigi, Narayan, Gopeshwar, Nandula, Subhadra V, Subramaniyam, Shivakumar, Kaufmann, Andreas M, Wright, Jason D, Pothuri, Bhavana, Mansukhani, Mahesh, Schneider, Achim, Arias-Pulido, Hugo, Murty, Vundavalli V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440550/
https://ncbi.nlm.nih.gov/pubmed/18559093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-58
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