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RNAi screening comes of age: improved techniques and complementary approaches

Gene silencing through sequence-specific targeting of mRNAs by RNAi has enabled genome-wide functional screens in cultured cells and in vivo in model organisms. These screens have resulted in the identification of new cellular pathways and potential drug targets. Considerable progress has been made...

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Bibliografski detalji
Glavni autori: Mohr, Stephanie E., Smith, Jennifer A., Shamu, Caroline E., Neumüller, Ralph A., Perrimon, Norbert
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204798/
https://ncbi.nlm.nih.gov/pubmed/25145850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3860
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