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RNAi screening comes of age: improved techniques and complementary approaches

Gene silencing through sequence-specific targeting of mRNAs by RNAi has enabled genome-wide functional screens in cultured cells and in vivo in model organisms. These screens have resulted in the identification of new cellular pathways and potential drug targets. Considerable progress has been made...

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Autors principals: Mohr, Stephanie E., Smith, Jennifer A., Shamu, Caroline E., Neumüller, Ralph A., Perrimon, Norbert
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204798/
https://ncbi.nlm.nih.gov/pubmed/25145850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3860
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