Potent interleukin 3 receptor agonist with selectively enhanced hematopoietic activity relative to recombinant human interleukin 3.

A systematic evaluation of structure-activity information led to the construction of genetically engineered interleukin 3 (IL-3) receptor agonists (synthokines) with enhanced hematopoietic potency. SC-55494, the most extensively characterized member of this series, exhibits 10- to 20-fold greater bi...

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Hlavní autoři: Thomas, J W, Baum, C M, Hood, W F, Klein, B, Monahan, J B, Paik, K, Staten, N, Abrams, M, McKearn, J P
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC42045/
https://ncbi.nlm.nih.gov/pubmed/7537376
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