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Synthetic CpG islands reveal DNA sequence determinants of chromatin structure

The mammalian genome is punctuated by CpG islands (CGIs), which differ sharply from the bulk genome by being rich in G + C and the dinucleotide CpG. CGIs often include transcription initiation sites and display ‘active’ histone marks, notably histone H3 lysine 4 methylation. In embryonic stem cells...

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書誌詳細
主要な著者: Wachter, Elisabeth, Quante, Timo, Merusi, Cara, Arczewska, Aleksandra, Stewart, Francis, Webb, Shaun, Bird, Adrian
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204011/
https://ncbi.nlm.nih.gov/pubmed/25259796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03397
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