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Synthetic CpG islands reveal DNA sequence determinants of chromatin structure
The mammalian genome is punctuated by CpG islands (CGIs), which differ sharply from the bulk genome by being rich in G + C and the dinucleotide CpG. CGIs often include transcription initiation sites and display ‘active’ histone marks, notably histone H3 lysine 4 methylation. In embryonic stem cells...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4204011/ https://ncbi.nlm.nih.gov/pubmed/25259796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03397 |
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