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Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine.

Cerebral infarction (stroke) is a potentially disastrous complication of diabetes mellitus, principally because the extent of cortical loss is greater in diabetic patients than in nondiabetic patients. The etiology of this enhanced neurotoxicity is poorly understood. We hypothesized that advanced gl...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zimmerman, G A, Meistrell, M, Bloom, O, Cockroft, K M, Bianchi, M, Risucci, D, Broome, J, Farmer, P, Cerami, A, Vlassara, H
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1995
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731977/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3744
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