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Polymorphism Ratio Sequencing: A New Approach for Single Nucleotide Polymorphism Discovery and Genotyping

Polymorphism ratio sequencing (PRS) combines the advantages of high-throughput DNA sequencing with new labeling and pooling schemes to produce a powerful assay for sensitive single nucleotide polymorphism (SNP) discovery, rapid genotyping, and accurate, multiplexed allele frequency determination. In...

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Detalhes bibliográficos
Main Authors: Blazej, Robert G., Paegel, Brian M., Mathies, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420372/
https://ncbi.nlm.nih.gov/pubmed/12566407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.396203
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