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Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation

A method for identifying and validating single nucleotide polymorphisms (SNPs) with high-density oligonucleotide arrays without the need for locus-specific polymerase chain reactions (PCR) is described in this report. Genomic DNAs were divided into subsets with complexity of ∼10 Mb by restriction en...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dong, Shoulian, Wang, Eugene, Hsie, Linda, Cao, Yanxiang, Chen, Xiaogiong, Gingeras, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC311102/
https://ncbi.nlm.nih.gov/pubmed/11483583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.171101
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