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Global RNA Half-Life Analysis in Escherichia coli Reveals Positional Patterns of Transcript Degradation

Subgenic-resolution oligonucleotide microarrays were used to study global RNA degradation in wild-type Escherichia coli MG1655. RNA chemical half-lives were measured for 1036 open reading frames (ORFs) and for 329 known and predicted operons. The half-life of total mRNA was 6.8 min under the conditi...

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Publicat a:Genome Res
Autors principals: Selinger, Douglas W., Saxena, Rini Mukherjee, Cheung, Kevin J., Church, George M., Rosenow, Carsten
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12566399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.912603
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