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Global RNA Half-Life Analysis in Escherichia coli Reveals Positional Patterns of Transcript Degradation

Subgenic-resolution oligonucleotide microarrays were used to study global RNA degradation in wild-type Escherichia coli MG1655. RNA chemical half-lives were measured for 1036 open reading frames (ORFs) and for 329 known and predicted operons. The half-life of total mRNA was 6.8 min under the conditi...

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Detalhes bibliográficos
Main Authors: Selinger, Douglas W., Saxena, Rini Mukherjee, Cheung, Kevin J., Church, George M., Rosenow, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420366/
https://ncbi.nlm.nih.gov/pubmed/12566399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.912603
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