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KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC
KIAA1524/CIP2A/cancerous inhibitor of protein phosphatase 2A is a cancer-promoting protein that stabilizes the MYC proto-oncogene protein by inhibiting its dephosphorylation. Our recent report demonstrates that KIAA1524/CIP2A supports cancer cell growth also at the level of the mechanistic target of...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203564/ https://ncbi.nlm.nih.gov/pubmed/24905455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29076 |
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