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SV40 T antigen interacts with Nbs1 to disrupt DNA replication control

Nijmegen breakage syndrome (NBS) is characterized by radiation hypersensitivity, chromosomal instability, and predisposition to cancer. Nbs1, the NBS protein, forms a tight complex with Mre11 and Rad50, and these interactions contribute to proper double-strand break repair. The simian virus 40 (SV40...

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Detalhes bibliográficos
Main Authors: Wu, Xiaohua, Avni, Dror, Chiba, Takuya, Yan, Feng, Zhao, Qiping, Lin, Yafang, Heng, Henry, Livingston, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420356/
https://ncbi.nlm.nih.gov/pubmed/15175262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1182804
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