PTK2 rs7460 and rs7843014 Polymorphisms and Exceptional Longevity: A Functional Replication Study

Focal adhesion is critical for cell survival. The focal adhesion kinase (FAK, or PTK2) is an important component of the human interactome and thus is a potential longevity-related protein. Here we studied the association between two PTK2 gene single-nucleotide polymorphisms (SNPs) (rs7843014, rs7460...

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Autori principali: Garatachea, Nuria, Fuku, Noriyuki, He, Zi-hong, Tian, Ye, Arai, Yasumichi, Abe, Yukiko, Murakami, Haruka, Miyachi, Motohiko, Yvert, Thomas, Venturini, Letizia, Santiago, Catalina, Santos-Lozano, Alejandro, Rodríguez, Gabriel, Ricevuti, Giovanni, Pareja-Galeano, Helios, Sanchis-Gomar, Fabian, Emanuele, Enzo, Hirose, Nobuyoshi, Lucia, Alejandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203112/
https://ncbi.nlm.nih.gov/pubmed/24930376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2014.1570
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