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N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation

Intracellular levels of the divalent cations Ca(2+) and Mg(2+) are important regulators of cell cycle and proliferation. However, the precise mechanisms by which they are regulated in cancer remain incompletely understood. The channel kinases TRPM6 and TRPM7 are gatekeepers of human Ca(2+)/Mg(2+) me...

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Detalhes bibliográficos
Main Authors: Zhang, Zheng, Faouzi, Malika, Huang, Junhao, Geerts, Dirk, Yu, Haijie, Fleig, Andrea, Penner, Reinhold
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202149/
https://ncbi.nlm.nih.gov/pubmed/25277194
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