N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation

Intracellular levels of the divalent cations Ca(2+) and Mg(2+) are important regulators of cell cycle and proliferation. However, the precise mechanisms by which they are regulated in cancer remain incompletely understood. The channel kinases TRPM6 and TRPM7 are gatekeepers of human Ca(2+)/Mg(2+) me...

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Autori principali: Zhang, Zheng, Faouzi, Malika, Huang, Junhao, Geerts, Dirk, Yu, Haijie, Fleig, Andrea, Penner, Reinhold
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202149/
https://ncbi.nlm.nih.gov/pubmed/25277194
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