TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma

In some tumours, despite a wild-type p53 gene, the p53 pathway is inactivated by alterations in its regulators or by unknown mechanisms, leading to resistance to cytotoxic therapies. Understanding the mechanisms of functional inactivation of wild-type p53 in these tumours may help to define prospect...

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Bibliografiske detaljer
Main Authors: Caratozzolo, Mariano Francesco, Valletti, Alessio, Gigante, Margherita, Aiello, Italia, Mastropasqua, Francesca, Marzano, Flaviana, Ditonno, Pasquale, Carrieri, Giuseppe, Simonnet, Hélène, D'Erchia, Anna Maria, Ranieri, Elena, Pesole, Graziano, Sbisà, Elisabetta, Tullo, Apollonia
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202135/
https://ncbi.nlm.nih.gov/pubmed/25277184
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